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Sr Director, Commercial Operations

Twist Bioscience · South San Francisco, California

$224,000–$289,000/yrOnsiteDirect from the employer

Posted Oct 7, 2026 · Verified open Oct 9, 2026

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About the job

Twist Bioscience is looking for a Director, Commercial Operations to lead, scale, and optimize key operating disciplines across our global commercial organization. In this role, you will lead cross-functional process improvements, oversee sales and project management operations, establish commercial reporting standards, and partner with executive leadership to drive scalable growth and an insights-driven sales approach.

What You’ll Be Doing

What You’ll Bring to the Team

Twist Bioscience is a leading synthetic biology and genomics company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip. Twist uses this platform to serve customers working in healthcare, agriculture, industrial chemicals, academic research and beyond, with products spanning synthetic genes and oligos, NGS target enrichment, and antibody discovery and development services.
The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.
San Francisco Bay Area Pay Range
$224,000 — $289,000 USD